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Table 2 Pregnancy outcome of control and Sofosbuvir-exposed mothers

From: The pre-conception maternal exposure to Sofosbuvir affects the mitochondrial biogenesis in prenatal fetal tissues: Experimental study on rats

Groups

Number of resorbed fetus/litter

Number of viable fetus/litter

Weight (g)

Fetal Crown-rump length (cm)

Fetus

Fetal placenta

Control

0.8 ± 0.42

13.2 ± 3.1

0.77 ± 0.09

0.38 ± 0.06

1.7 ± 0.14

Sofosbuvir exposed

3.8* ± 1.7

9.4 ± 2.9

1.68* ± 0.36

0.47* ± 0.08

2.33* ± 0.24

% of change from control

375

− 28.8

118.1

35.13

37

  1. Data were illustrated as Mean ± SD
  2. Number of fetuses in each group = 10
  3. g gram
  4. cm centimeter
  5. *p < 0.05, indicating a statistically significant difference when compared with the control group using independent sample t-test
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Molecular Medicine

ISSN: 1528-3658