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Table 3 The change of Malondialdehyde (MDA) content in the studied fetal tissues

From: The pre-conception maternal exposure to Sofosbuvir affects the mitochondrial biogenesis in prenatal fetal tissues: Experimental study on rats

Groups

MDA (nmol/mg protein)

Fetal liver

Fetal muscle

Fetal placenta

Control

0.78 ± 0.039

1.7 ± 0.32

0.30 ± 0.034

Sofosbuvir exposed

1.36* ± 0.15

4.15* ± 0.22

2.33* ± 0.39

% of change from control

74.3

144.1

667.6

  1. Data were illustrated as Mean ± SD
  2. Number of fetuses in each group = 10
  3. MDA Malondialdehyde
  4. *p < 0.05, indicating a statistically significant difference when compared with the control group using independent sample t-test
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Molecular Medicine

ISSN: 1528-3658