Fig. 1
From: IL-33/ST2 axis of human amnion fibroblasts participates in inflammatory reactions at parturition
Expression of IL-33 and ST2 in human amnion at term and preterm labor. (A and B) Abundance of IL33 and IL1RL1 gene transcripts in the amnion in the TL (term labor, n = 3) and TNL (term non-labor, n = 3) groups as revealed by transcriptomic sequencing. FPKM, fragments per kilo base per million mapped reads. (C and D) Abundance of IL33 and IL1RL1 mRNA in the amnion of the TL (n = 9) and TNL (n = 8) groups as measured with qRT-PCR. (E and F) Abundance of IL33 and IL1RL1 mRNA in the amnion of the PL (preterm labor, n = 9) and PNL (preterm non-labor, n = 7) groups as measured with qRT-PCR. (G) Abundance of IL-33 and ST2 protein in the amnion of the TL (n = 7) and TNL (n = 7) groups as measured with Western blotting. (H) Abundance of IL-33 and ST2 protein in the amnion of the PL (n = 11) and PNL (n = 8) groups as measured with Western blotting. Top panels are the representative immunoblots. Data are mean ± SEM. Statistical analysis was performed with the Mann–Whitney U test. *p < 0.05, **p < 0.01 vs. TNL or PNL