Fig. 8
From: IL-33/ST2 axis of human amnion fibroblasts participates in inflammatory reactions at parturition
Induction of preterm birth by IL-33 in pregnant mice. (A) Time-line illustrating the procedure of IL-33 administration in pregnant mice. i.p., intraperitoneal injection. (B) Preterm birth rate in IL-33 administration (n = 11) and vehicle control (n = 6) group. (C and D) COX-2 protein abundance in the fetal membranes collected from IL-33 (n = 6) and vehicle control (n = 6) groups. C is the immunoblot, D is the average data. (E and F) IL-1β and IL-6 abundance in the fetal membranes collected from IL-33 (n = 5) and vehicle control (n = 6) groups. Data are mean ± SEM. Statistical analysis was performed with unpaired Student’s t-test. *p < 0.05, ***p < 0.001 vs. vehicle control