Fig. 4
From: ERRα protects against sepsis-induced acute lung injury in rats
ERRα activation inhibits CLP-induced ALI in vivo. A. H&E staining showed morphological changes in lung tissues after CLP. Scale bar, 50 μm. B-C. RT-PCR (B), Western blot and quantitative analysis (C) of ERRα expression in Sham and CLP groups. D-E. RT-PCR (D), Western blot and quantitative analysis (E) showed that 16054-93-6 promoted the expression of ERRα in a dose-dependent manner in CLP-treated rats. F. Lung dry to wet weight ratio showed the degree of pulmonary edema. G. Total cell count in bronchoalveolar lavage fluid (BALF). H. Representative H&E staining micrographs showed the pathological damage of lung tissues in four groups as indicated. Scale bar, 50 μm. Values are expressed as mean ± SD. *P < 0.05 versus the Sham group; #P < 0.05 versus the CLP group