Fig. 5
From: ERRα protects against sepsis-induced acute lung injury in rats
Promoting ERRα expression reduces the CLP-induced degradation of junction protein and lung vascular hyperpermeability. A. Representative micrograph of IHC showed lung VE-cadherin expression (solid arrow) in four groups as indicated. Scale bar, 25 μm. B. Pulmonary vascular permeability was compared by Evans blue dye extravasation in four groups. C. Western blot and quantitative analysis of ZO-1, Occludin, JAM-A, and VE-cadherin in the four groups. Values are expressed as mean ± SD. *P < 0.05 versus the Sham group; #P < 0.05 versus the CLP group