Fig. 6
From: ERRα protects against sepsis-induced acute lung injury in rats
ERRα has a dual protective effect in CLP-induced ALI. Representative micrographs of IHC showed lung cleaved caspase 3 expression in four groups as indicated. Scale bar, 25 μm. B. Representative blots and quantitative analysis showing the relative protein levels of apoptosis-associated proteins in different groups. C. Immunofluorescence showing the changes of LC3B (green) and p62 (red) expression from agonist-treated rats after CLP, observed by confocal microscopic images. White arrows indicate colocalization expression. Scale bar, 50/3µm. D. Representative blots and quantitative analysis showing the relative protein levels of autophagy-associated proteins in different groups. E. Representative blots and quantitative analysis showing the expression levels of Sirt 3 in different groups. Values are expressed as mean ± SD. *P < 0.05 versus Sham group; #P < 0.05 versus the CLP group