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Fig. 2 | Molecular Medicine

Fig. 2

From: 5α-Hydroxycostic acid inhibits choroidal neovascularization in rats through a dual signalling pathway mediated by VEGF and angiopoietin 2

Fig. 2

5α-Hydroxycostic acid inhibited VEGFR2, Ang2, Tie2 mRNA levels and increased VE-cadherin, ZO-1 mRNA levels. a Inhibition of VEGF-induced RCSECs tube formation by 5α-Hydroxycostic acid.Cell tubular structures were captured (magnification, ×100) and tube length was quantified (n = 3). b mRNA expression levels in control group, VEGF group, and VEGF + 5α-Hydroxycostic acid group. The results are presented as the mean ± SD. n = 3; *P < 0.05, **P < 0.01, ***P < 0.001

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Molecular Medicine

ISSN: 1528-3658