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Fig. 3 | Molecular Medicine

Fig. 3

From: 5α-Hydroxycostic acid inhibits choroidal neovascularization in rats through a dual signalling pathway mediated by VEGF and angiopoietin 2

Fig. 3

5α-Hydroxycostic acid inhibits angiogenesis by reducing the production of angiogenic factors to enhance intercellular adhesion. af The relative protein levels of VEGFR2, p-VEGFR2, Ang2, Tie2, p-Tie2, VE-cadherin and ZO-1 in each group were detected by Western blot. g, h Immunostaining analysis of VE-cadherin in three groups of cells (magnification, ×200). The results are presented as the mean ± SD. n = 3; *P < 0.05, **P < 0.01, ***P < 0.001

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