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Fig. 5 | Molecular Medicine

Fig. 5

From: 5α-Hydroxycostic acid inhibits choroidal neovascularization in rats through a dual signalling pathway mediated by VEGF and angiopoietin 2

Fig. 5

5α-Hydroxycostic acid can treat rat choroidal neovascularization and reduce neovascularization and leakage. a At day 14 after photocoagulation, fundus fluorescein angiography (FFA) was performed to evaluate CNV formation. b, c Choroidal patches and the area of choroidal neovascular leakage in CNV group, 5α-Hydroxycostic acid treatment groupand Semaxinib treatment group (magnification, ×200). d Hematoxylin–eosin (HE) staining observed the structural changes of retina and choroid in rats after treatment (magnification, ×100). The results are presented as the mean ± SD. n = 3; ***P < 0.001

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Molecular Medicine

ISSN: 1528-3658