Skip to main content
Fig. 6 | Molecular Medicine

Fig. 6

From: 5α-Hydroxycostic acid inhibits choroidal neovascularization in rats through a dual signalling pathway mediated by VEGF and angiopoietin 2

Fig. 6

5α-Hydroxycostic acid plays an anti-neovascularization role by regulating VEGF/VEGFR and Ang2/Tie2 signaling pathways. The rats (n = 15) were randomly divided into four groups: control group, CNV group, 5α-Hydroxycostic acid treatment group (CNV + 5α-Hydroxycostic acid), and Semaxinib treatment group. a–f The protein levels of VEGFR2, p-VEGFR2, Ang2, Tie2, p-Tie2, VE-cadherin and ZO-1 in choroid tissues were determined by western blot. The results are presented as the mean ± SD. n = 3; **P < 0.01, ***P < 0.001

Back to article page

Molecular Medicine

ISSN: 1528-3658