Fig. 1
From: Regulatory mechanisms and therapeutic potential of JAB1 in neurological development and disorders
The profile of JAB1 protein. A The bootstrap consensus phylogenetic tree of JAB1 proteins from different species. The phylogenetic tree was constructed by using MEGA software version 11.0.13. B Human JAB1 amino acid sequences. MPN, NES, and C-terminal domains are shown in yellow, red, and cyan, respectively. JAMM motif is marked by a black box. C The structure of human JAB1 is shown based on the data from Protein Data Bank (ID 4D18; https://www.rcsb.org/structure/4D18). MPN, NES, and C-terminal domains are shown in yellow, red, and cyan, respectively. JAMM motif is exhibited by ball and sticks