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Fig. 2 | Molecular Medicine

Fig. 2

From: High mobility group box 1 and a network of other biomolecules influence fatigue in patients with Crohn’s disease

Fig. 2

Model including fVAS in an unsupervised principal component analysis of 52 patients with Crohn’s disease showing the orientation and contribution of selected biomolecules measured in plasma. The individual points are colored according to the individuals’ fVAS scores. Component 1 is the “inflammation and cellular stress dimension” and Component 2 is the “HMGB1 dimension”. abs antibodies, frHMGB1 fully reduced HMGB1, fVAS fatigue visual analogue scale, HMGB1 high mobility group box 1, HPX hemopexin, HSP heat shock protein, IL-1RA interleukin-1 receptor antagonist, sIL-1RII soluble interleukin-1 receptor type 2, PEDF pigment epithelium-derived factor

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Molecular Medicine

ISSN: 1528-3658