Fig. 1From: Improved intravenous lentiviral gene therapy based on endothelial-specific promoter-driven factor VIII expression for hemophilia AThe NHP/TYF F8BDD LV system with an universal promoter and tissue-specific promoters for ECs and megakaryocytes. A Schematic illustration of self-inactivating LVs encoding the partially sequence-optimized human F8BDD gene. B Schematic illustration of the LV-F8BDD under the control of different promoters as depictedBack to article page