Fig. 2
From: PAX5-miR-142 feedback loop promotes breast cancer proliferation by regulating DNMT1 and ZEB1
PAX5 inhibited breast cancer proliferation by targeting miR-142-5p/3p. A The construction of PAX5-overexpressed miR-142-5p-delepted (left) and PAX5-overexpressed miR-142-3p-delepted (right) MDA-231 cells verified by qRT-PCR. The cell proliferation assays were conducted, including colony formation assay (B), MTT assay (C) and EdU assay (D). E The distribution of cell cycle was detected by flow cytometry. F Representative photos and growth curve of tumors. G The H&E staining and Ki-67 expression levels of xenograft tumors detected by IHC. *p < 0.05