Fig. 3
From: PAX5-miR-142 feedback loop promotes breast cancer proliferation by regulating DNMT1 and ZEB1
PAX5 was hypermethylated by DNMT1. A The existence of CpG island on PAX5 promoter region predicted by Meth primer. B The methylation status of breast cancer cells detected by BSP sequencing. The expression level of PAX5 after the treatment of AZA in breast cancer cell lines by qRT-PCR (C), and western blot (D). The interaction of DNMT1 and PAX5 detected by ChIP analysis. *p < 0.05