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Fig. 2 | Molecular Medicine

Fig. 2

From: Decreased expression of H19/miR-675 ameliorates muscle atrophy by regulating the IGF1R/Akt/FoxO signaling pathway

Fig. 2

Effect of H19/miR-675 on Atrogin-1 expression in vitro. a Real-time PCR analysis of the expression of H19, miR-675-3p, and miR-675-5p in C2C12 cells treated with H19 overexpression plasmid (n = 3). b Real-time PCR analysis of the expression of Atrogin-1 mRNA in C2C12 cells transfected with H19 overexpression plasmid either alone or in combination with miR-675 inhibitors (n = 3). c Real-time PCR analysis of the expression of H19, miR-675-3p, and miR-675-5p in C2C12 cells treated with H19 smart silencer (n = 3). All data are shown as mean ± SD. *P < 0.05 and **P < 0.01 compared to control groups

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Molecular Medicine

ISSN: 1528-3658