Skip to main content
Fig. 5 | Molecular Medicine

Fig. 5

From: Decreased expression of H19/miR-675 ameliorates muscle atrophy by regulating the IGF1R/Akt/FoxO signaling pathway

Fig. 5

Effect of miR-675 on the IGF1R/Akt/FoxO signaling pathway during muscle atrophy. Western blotting analysis of IGF1R, pAKT, and FoxO3a in C2C12 myotubes transfected with miR-675 mimics a or inhibitor c and their negative controls (n = 3). Western blotting analysis of IGF1R, pAKT, and FoxO3a in gastrocnemius muscles transfected with miR-675 agomiR b or antagomiR d and their negative controls (n = 6). All data are shown as mean ± SD. *P < 0.05 and **P < 0.01 compared to the control groups

Back to article page

Molecular Medicine

ISSN: 1528-3658