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Fig. 1 | Molecular Medicine

Fig. 1

From: HOXA1 participates in VSMC-to-macrophage-like cell transformation via regulation of NF-κB p65 and KLF4: a potential mechanism of atherosclerosis pathogenesis

Fig. 1

HOXA1 expression is increased in the aortic root of AS mice. A Oil red-O staining for the aortic root of wild-type mice with ND, wild-type mice with HFD, or ApoE−/− mice with HFD. Scale bar = 500 μm (40 ×). B Immunofluorescence double staining for HOXA1 (red) and α-SMA (green) in each group. DAPI (blue) was used for nucleus staining. Scale bar = 50 μm (400 ×). C Western blot for HOXA1 expression in aortic root of wild-type or HFD-fed ApoE−/− mice. Data are expressed as mean ± SD (6 animals/group). Ordinary one-way ANOVA followed by Tukey's multiple comparison test was used to calculate the P value in panel C ***P < 0.001

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Molecular Medicine

ISSN: 1528-3658