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Fig. 4 | Molecular Medicine

Fig. 4

From: HOXA1 participates in VSMC-to-macrophage-like cell transformation via regulation of NF-κB p65 and KLF4: a potential mechanism of atherosclerosis pathogenesis

Fig. 4

Silencing of HOXA1 reduces atherosclerotic lesions of AS mice. A Oil red-O, HE, and PSR staining for thoracic aorta or aortic root sections of mice in each group. Scale bar = 500 μm (40 ×); Quantification for lipid content (Oil red-O, panel B), necrotic core area (HE, panel C) and collagen content (PSR, panel D). Data are expressed as mean ± SD (6 animals/group). Ordinary one-way ANOVA followed by Tukey's multiple comparison test was used to calculate the P value in panel B–D. *P < 0.05, **P < 0.01, ***P < 0.001

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Molecular Medicine

ISSN: 1528-3658