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Fig. 2 | Molecular Medicine

Fig. 2

From: Acetylcholinesterase inhibition protects against trastuzumab-induced cardiotoxicity through reducing multiple programmed cell death pathways

Fig. 2

The effects of donepezil on left ventricular function and blood pressure in TIC rats. a LVEF; b Representative images of echocardiography; c E/A ratio; d SBP; e DBP; f SV; g LVESP; h LVEDP; i dp/dtmax; j dp/dtmin. DBP diastolic blood pressure; DPZ donepezil; dp/dtmax the maximum time derivative of LV pressure; dp/dtmin the minimum time derivative of LV pressure; E/A early filling to atrial filling velocities; SBP systolic blood pressure; SV stroke volume; Trz trastuzumab. n = 6–8 rats per group. Data are presented as the mean ± SEM; *p < 0.05 vs. control; #p < 0.05 vs. Trz

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