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Fig. 3 | Molecular Medicine

Fig. 3

From: Acetylcholinesterase inhibition protects against trastuzumab-induced cardiotoxicity through reducing multiple programmed cell death pathways

Fig. 3

The effects of donepezil on cardiac autonomic function in rats treated with Trz. a HR; b LF (normalized unit); c HF (normalized unit); d LF/HF ratio; e Serum AChE activity. AChE acetylcholinesterase; DPZ donepezil; HF high-frequency component; HR heart rate; LF low-frequency component; Trz trastuzumab. n = 6–8 rats per group. Data are presented as the mean ± SEM; *p < 0.05 vs. control; #p < 0.05 vs. Trz

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