Table 1 DEGs previously reported to be associated with placental development and pathology

Tubb3

Preeclampsia

1.632

doi: https://doi.org/10.3390/biology9040062.

Tpbpa

Defects in maternal spiral artery remodeling

0.585

doi: https://doi.org/10.1016/j.ydbio.2011.07.036.

Mmp12

Preeclampsia

0.654

doi: https://doi.org/10.1016/j.placenta.2008.09.015.

Ppp2r2c

Preeclampsia

1.587

doi: https://doi.org/10.1016/j.tjog.2011.07.005.

Cd83

Preeclampsia

0.619

doi: https://doi.org/10.1371/journal.pone.0180065

Hspb11

Preeclampsia

0.593

doi: https://doi.org/10.7150/thno.56141.

Iqgap3

Preeclampsia

1.580

doi: https://doi.org/10.7150/thno.56141.

Drd4

Preeclampsia

1.546

doi: https://doi.org/10.7150/thno.56141.

Krtcap3

Preeclampsia

1.684

doi: https://doi.org/10.14288/1.0074068

1600015I10Rik

Maternal hypoxia

0.311

doi: https://doi.org/10.1177/1933719107302860.

Eya4

Preeclampsia, IUGR

0.582

doi: https://doi.org/10.14288/1.0361940

Kcnk2

Preeclampsia, IUGR

0.538

doi: https://doi.org/10.14288/1.0361940

Susd3

Stillbirths

2.529

doi: https://doi.org/10.1002/pd.2817.

Il23r

IUGR

0.542

doi: https://doi.org/10.1016/j.nutres.2016.08.001.

Vcan

Preeclampsia

0.647

doi: https://doi.org/10.1371/journal.pone.0178549.

Rnf222

Maternal obesity

1.563

doi: https://doi.org/10.1038/s41366-020-0561-3.

Grhpr

Preeclampsia

1.511

doi: https://doi.org/10.3389/fphys.2020.592689.

Slc5a5

Recurrent pregnancy loss/failures

1.571

doi: https://doi.org/10.1159/000508309.

Pdk4

IUGR

0.660

doi: https://doi.org/10.1152/ajpregu.00197.2015.

Cdh23

Preeclampsia

1.576

doi: https://doi.org/10.1371/journal.pone.0222672.

Tpbpb

Gestational Diabetes Mellitu

0.576

doi: https://doi.org/10.1371/journal.pone.0038445.

Kcnk2

Gestational Diabetes Mellitu

0.538

doi: https://doi.org/10.1371/journal.pone.0038445.

Ccl2

IUGR

2.036

doi: https://doi.org/10.1016/j.ajog.2013.03.001.

Slc2a3

IUGR

1.568

doi: https://doi.org/10.1113/JP278473.

Timp1

Preeclampsia

1.792

doi: https://doi.org/10.1095/biolreprod.107.063743.

Lin9

preterm labour

0.646

doi: https://doi.org/10.1186/s12916-016-0632-4.

Sfrp1

preterm birth

0.659

doi: https://doi.org/10.1080/14767058.2017.1359830.

Retnlg

IUGR

2.289

https://doi.org/10.1101/2021.03.26.437292

S100a9

IUGR

1.924

https://doi.org/10.1101/2021.03.26.437292

Ccl2

Preeclampsia

2.036

doi: https://doi.org/10.3390/biom10060953.

Fbxo2

Preeclampsia, IUGR

1.569

doi: https://doi.org/10.3390/ijms21103597.

Fstl3

Preeclampsia

1.600

doi: https://doi.org/10.1186/s12920-019-0548-x.

Dnm1

Preeclampsia

1.535

doi: https://doi.org/10.1186/1752-0509-6-97.

Tff3

Preeclampsia

1.815

doi: https://doi.org/10.1080/14767058.2021.1888915.

Pros1

Preeclampsia

0.634

doi: https://doi.org/10.3892/ijmm.2012.983.

Uchl3

Preeclampsia

0.662

doi: https://doi.org/10.3892/ijmm.2012.983.

Mfsd2a

Gestational Diabetes Mellitus, Preeclampsia

1.644

doi: https://doi.org/10.3390/nu11051107.

Kcnj15

Preeclampsia

0.566

doi: https://doi.org/10.1038/s41598-020-79008-4.

Kcnq4

Preeclampsia

1.719

doi: https://doi.org/10.1371/journal.pone.0192122.

Ceacam13

IUGR

0.529

doi: https://doi.org/10.1055/s-0029-1224143.

DEGs in male

Gene symbol

Related to

Fold change

References (doi)

Krt80

Preeclampsia

0.598

doi: https://doi.org/10.3390/biology9040062.

Fxyd1

preeclampsia

0.347

doi: https://doi.org/10.1016/j.ajog.2010.08.043

Col7a1

IUGR

1.741

doi: https://doi.org/10.1016/j.jri.2010.04.001.

Rasl11b

Preeclampsia

0.632

doi: https://doi.org/10.7150/thno.56141.

Slc37a1

Preeclampsia

0.503

doi: https://doi.org/10.1101/2021.03.11.21253393

1600015I10Rik

Maternal hypoxia

0.330

doi: https://doi.org/10.1177/1933719107302860.

Trib3

Preeclampsia, IUGR

0.578

doi: https://doi.org/10.14288/1.0361940

Birc7

Gestational Diabetes Mellitu

0.633

doi: https://doi.org/10.1016/j.jdiacomp.

Add2

Gestational Diabetes Mellitu

0.591

doi: https://doi.org/10.1016/j.ajog.2008.08.022.

Slc30a3

Preterm birth

0.627

doi: https://doi.org/10.17077/etd.p3zuvpa3

Kcnk2

Gestational Diabetes Mellitu

0.556

doi: https://doi.org/10.1371/journal.pone.0038445.

Ccl2

IUGR

2.105

doi: https://doi.org/10.1016/j.ajog.2013.03.001.

Timp1

Preeclampsia

1.358

doi: https://doi.org/10.1095/biolreprod.107.063743.

Atf5

Early-onset preeclampsia

0.622

doi: https://doi.org/10.1073/pnas.1907548116.

Retnlg

IUGR

2.289

https://doi.org/10.1101/2021.03.26.437292

S100a9

IUGR

1.924

https://doi.org/10.1101/2021.03.26.437292

Scgb1a1

IUGR

0.623

https://doi.org/10.1101/2021.03.26.437292

Ccl2

Preeclampsia

2.105

doi: https://doi.org/10.3390/biom10060953.

Gpnmb

preeclampsia

0.599

doi: https://doi.org/10.1080/14767058.2021.1888915.

Ctf1

preeclampsia

1.547

doi: https://doi.org/10.1074/jbc.M111.230045.

1810011O10Rik

Preeclampsia

0.657

doi: https://doi.org/10.3892/ijmm.2012.983.

Mgat3

Preeclampsia

0.666

doi: https://doi.org/10.3892/ijmm.2012.983.

F11

IUGR

0.586

doi: https://doi.org/10.1038/s41598-018-37627-y.

Angpt2

preeclamsia

0.594

doi: https://doi.org/10.1016/j.placenta.2014.07.001.