Skip to main content

Table 3 Alterations in the preterm infant gut microbiota related to feeding type

From: Determinants of microbial colonization in the premature gut

Reference

Region

Sample size (n)

Sample time

Alterations in the GMa of PTIs

MOM

DHM

Formula

 

MOM

DHM

Formula

Ford, et al. (2019)

USA

74

43

-

Within 6 weeks after birth

↑Alpha-diversity

 

-

Week 4

↑Bacteroides, Bifidobacterium, and Enterococcus

↑Staphylococcus

-

Parra-Llorca, et al. (2018)

Spain

34

28

7

By the time of full enteral feeding

↓Clostridiaceae, ↑Bifidobacterium, Staphylococcus, Clostridium, Serratia, Coprococcus, Aggregatibacter, and Lactobacillus

↓Actinobacteria, ↑Bacteroidetes

-

 

Acinetobacter genus was found

Bacteroidetes was highest; Staphylococcus and Klebsiella were dominant

Gregory, et al. (2016)

USA

10

10

10

First 60 days

Initial increase in diversity

 

Lactobacillales was highest

Wang, et al. (2020)

USA

10

-

10

At an average of 15 and 17 days after birth

Veillonella, Escherichia/Shigella, Staphylococcus, Clostridium, Enterococcus, and Streptococcus were dominant

-

↓Proteobacteria

  1. aGM, gut microbiota; PTIs, preterm infants; MOM, mother’s own milk; DHM, donor human milk