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Fig. 5 | Molecular Medicine

Fig. 5

From: Therapeutic effects of engineered exosome-based miR-25 and miR-181a treatment in spinocerebellar ataxia type 3 mice by silencing ATXN3

Fig. 5

Exosomal miRNA treatment reduced the neuron apoptosis in the DCN without increasing the neuro-inflammatory response. (A, B) Histological and quantitative analysis of NeuN positive cells in the DCN 4 weeks after initial injection. (A, C) Immunofluorescent staining and quantitative analysis of the fluorescence intensity of GFAP 4 weeks after initial injection. Scale bar = 50 μm. *<0.05, **<0.01

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Molecular Medicine

ISSN: 1528-3658