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Fig. 3 | Molecular Medicine

Fig. 3

From: Restoring Wnt signaling in a hormone-simulated postpartum depression model remediated imbalanced neurotransmission and depressive-like behaviors

Fig. 3

Hormone withdrawal decreased the plasticity of excitatory and inhibitory synapses in the hippocampus. a, b Relative expression of p-GluA1(Ser845), GluA1, and PSD95 in the hippocampus. c The expression of p-GluA1 (Ser845)/GluA1 ratio of three groups. d, e Relative expression of the γ2, δ, and α5 subunits of GABAARs in each group in total hippocampal protein level. f, g Relative expression of the γ2, δ, and α5 subunits of GABAARs in each group in membrane hippocampal protein level. All the expression of the protein was standardized by the HSP group. All data were assessed with One-way ANOVA. Tukey's multiple comparisons test was performed in comparison of SHAM versus the HSPP group. Dunnett's multiple comparisons test was performed in comparison of the HSP versus SHAM and the HSP versus the HSPP group. Data represent means ± SEM. *p<0.05, **p<0.005, ***p<0.001

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