Fig. 4
From: SBP1 promotes tumorigenesis of thyroid cancer through TXN/NIS pathway
SBP1 interacts with TXN. (A) Immunohistochemistry staining of TXN in primary thyroid cancer and matched noncancerous thyroid tissue. (B) TXN expression was determined by Western blot analysis in 6 pairs of primary thyroid cancer and their matched noncancerous thyroid tissues. (C) The level of TXN in thyroid patients was analyzed. (D) Expression of TXN was positively correlated with thyroid cancer stage. (E) Western blot assays were performed to assess protein expression of TXN in BHT101 cells transfected with si-SBP1. (F) Western blot assays were performed to assess protein expression of TXN in FTC-133 cells transfected with SBP1 overexpression vector. (G) SBP1 was positively correlated with TXN expression in 12 thyroid cancer tissues. (H) Interaction of SBP1 and TXN in BHT101 cells was analyzed by co-immunopercipient. *P < 0.05. T, tumor; N, normal; si-NC, negative control siRNA; NC, negative control