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Table 1 Characteristics of the overall population (n = 246)

From: Polymorphic variants at NDUFC2, encoding a mitochondrial complex I subunit, associate with cardiac hypertrophy in human hypertension

General data

 

Age, years

59 ± 15

Male sex, n (%)

144 (58.6)

BMI, Kg/m2

25.7 ± 3.6

Diabetes, n (%)

41 (16.7)

Dyslipidaemia, n (%)

97 (40)

Clinic SBP, mmHg

145.6 ± 16.9

Clinic DBP, mmHg

87.1 ± 9.8

24 h mean SBP, mmHg

129.1 ± 13.1

24 h mean DBP, mmHg

78.1 ± 8.9

Echocardiographic data

 

Septal thickness, mm

10.1 ± 1.6

LVPW, mm

9.8 ± 1.6

RWT

0.41 ± 0.06

LVEDd, mm

48.6 ± 4.1

LV mass, g

172.1 ± 47.9

LV mass/BSA, g/m2

93.2 ± 23.8

LV mass/h2,7, g/m2,7

39.6 ± 13.1

LA vol/h2, ml/m2

15.3 ± 3.4

LVEF, %

67.5 ± 9.7

Pharmacological therapy

 

ACEi, n (%)

46 (18.6)

ARB, n (%)

111 (45)

Calcium channel blockers, n (%)

93 (37.7)

Thiazide diuretics, n (%)

64 (26)

Beta-blockers, n (%)

55 (22.5)

MRA, n (%)

11 (4.3)

Combination therapy, n (%)

126 (51)

2 drugs, n (%)

88 (35.6)

3 drugs, n (%)

27 (11)

4 drugs, n (%)

11 (4.5)

  1. ACEi, angiotensin converting enzyme inhibitors; ARB, angiotensin receptor blockers; BMI, body mass index; DBP, diastolic blood pressure; LA, left atrium; LV, left ventricle; LVEDd, left ventricular end-diastolic diameter; LVEF, left ventricular ejection fraction; LVPW, left ventricular posterior wall; MRA, mineracolorticoid receptor antagonists; RWT, relative wall thickening; SBP, systolic blood pressure