Polymorphic variants at NDUFC2, encoding a mitochondrial complex I subunit, associate with cardiac hypertrophy in human hypertension

Table 3 Genotype and allele frequencies distribution for rs641836 and rs11237379 NDUFC2 polymorphisms in hypertensive patients with and without LVH

SNP	Patients without LVH (n = 167) n (%)	Patients with LVH (n = 79) n (%)	p-value
rs641836
GG	114 (68.2)	39 (49.4)	0.004
GA	50 (29.9)	34 (43)	0.047
AA	3 (1.8)	6 (7.5)	0.034
A frequency	0.167	0.291	0.007
H-W	0.47	0.12
rs11237379
TT	43 (25.7)	32 (40.5)	0.017
TC	96 (57.4)	34 (43)	0.019
CC	28 (16.7)	13 (16.4)	0.513
T frequency	0.545	0.62	0.048
H-W	2.56	0.69

H-W, Hardy Weinberg; LVH, left ventricular hypertrophy; SNP, single nucleotide polymorphism

ISSN: 1528-3658