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Fig. 2 | Molecular Medicine

Fig. 2

From: Elevated galectin-3 levels detected in women with hyperglycemia during early and mid-pregnancy antagonizes high glucose − induced trophoblast cells apoptosis via galectin-3/foxc1 pathway

Fig. 2

Effects of different glucose concentrations on the expression levels of galectin-3 and foxc1. (A) Expression of galectin-3 in human placenta of hyperglycemia in pregnancy (HIP, n = 4) and healthy pregnant women (HP, n = 4). Abundant expression of galectin-3 protein observed in cytotrophoblast (CTB) (arrows). (B) Relative mRNA expression levels of galectin-3 determined by RT-qPCR in HTR-8/SVneo cells (left panel). Expression of galectin-3 protein levels measured by western blotting in HTR-8/SVneo cells (middle and right panels). (C) Relative mRNA expression levels of foxc1 determined by RT-qPCR in HTR-8/SVneo cells (left panel). Expression of foxc1 protein levels measured by western blotting in HTR-8/SVneo cells (middle and right panels). *: P < 0.05, **: P < 0.01, and ***: P < 0.001

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Molecular Medicine

ISSN: 1528-3658