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Fig. 6 | Molecular Medicine

Fig. 6

From: Elevated galectin-3 levels detected in women with hyperglycemia during early and mid-pregnancy antagonizes high glucose − induced trophoblast cells apoptosis via galectin-3/foxc1 pathway

Fig. 6

Foxc1 antagonized high glucose (25 mM) − induced trophoblast cells apoptosis. (A) Western blotting analysis showing expression of pro-apoptosis markers (active caspase-3 and total caspase-3) with foxc1 siRNA. (B) The percentages of apoptosis (early apoptosis, late apoptosis, and early apoptosis plus late apoptosis) of HTR-8/SVneo cells were measured by flow cytometry after treatment with foxc1-siRNA-1409. Q1, necrotic cells; Q2, late apoptosis cells; Q3, living cells; Q4, early apoptosis cells. *: P < 0.05, **: P < 0.01, and ***: P < 0.001

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Molecular Medicine

ISSN: 1528-3658