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Fig. 5 | Molecular Medicine

Fig. 5

From: AQP3-mediated activation of the AMPK/SIRT1 signaling pathway curtails gallstone formation in mice by inhibiting inflammatory injury of gallbladder mucosal epithelial cells

Fig. 5

Effects of AQP3 on AMPK/SIRT1 signaling pathway in LPS-induced gallbladder mucosal epithelial cells. A RT-qPCR to detect the mRNA expression of SIRT1 in LPS-induced gallbladder mucosal epithelial cells after AQP3 overexpression. B, Western blot to detect the protein expression and phosphorylation level of AMPK and protein expression of SIRT1 in LPS-induced gallbladder mucosal epithelial cells after AQP3 overexpression. All cell experiments were repeated three times. * p < 0.05

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