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Fig. 2 | Molecular Medicine

Fig. 2

From: BAP1 mutations inhibit the NF-κB signaling pathway to induce an immunosuppressive microenvironment in uveal melanoma

Fig. 2

Correlation analysis between TMB values and clinicopathological characteristics and prognosis of UM patients. A, Mutation types and frequency of mutated genes in UM samples, and TMB value of each sample. The green region indicates the missense mutations, blue region indicates the frameshift deletion mutations, the red region indicates the nonsense mutations, the yellow region indicates the in-frame deletion mutations, the purple region indicates the frameshift insertion mutation, the black region indicates multiple mutations and the gray region indicates no mutations. B, Correlation between clinicopathological characteristics (clinical stage, grade and gender) and TMB value of UM patients. C, Survival analysis of UM patients in the high TMB group and the low TMB group. The red line indicates the UM patients in the high TMB group, and the blue line represents the UM patients in the low TMB group

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Molecular Medicine

ISSN: 1528-3658