Fig. 10

Fer-1 counteracted the effects of Metrnβ knockdown in vivo. Mice were treated with Ad-shMetrnβ, Fer-1 and LPS. A H&E staining of lung tissue after LPS challenge (n = 6). B Lung wet and dry weight ratio (W/D ratio) in mice challenged with LPS (n = 6). C Lung injury score in mice challenged with LPS (n = 6). D Levels of proinflammatory markers in lung tissue after LPS challenge (n = 6). E MDA levels in LPS-induced lung tissue (n = 6). F GSH levels in LPS-induced lung tissue (n = 6). G Fe²⁺ levels in LPS-induced mouse lung tissue (n = 6). *P < 0.05 vs. the CON group. #P < 0.05 vs. the LPS group. NS no significant