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Fig. 2 | Molecular Medicine

Fig. 2

From: Meteorin-like/Meteorin-β protects LPS-induced acute lung injury by activating SIRT1-P53-SLC7A11 mediated ferroptosis pathway

Fig. 2

Metrnβ overexpression ameliorated LPS-induced ALI and ferroptosis. A Protein level of Metrnβ in mice treated with Ad-Metrnβ and challenged with LPS (n = 4). B H&E staining of lung tissue after LPS challenge (n = 6). C Lung wet and dry weight ratio (W/D ratio) in mice challenged with LPS (n = 6). D Lung injury score in mice challenged with LPS (n = 6). E Proinflammatory markers in lung tissue after LPS challenge (n = 6). F MDA levels in LPS-induced lung tissue (n = 6). G GSH levels in LPS-induced lung tissue (n = 6). H Fe2+ levels in LPS-induced mouse lung tissue (n = 6). *P < 0.05 vs. the NC-CON group. #P < 0.05 vs. the NC-LPS group

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