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Fig. 6 | Molecular Medicine

Fig. 6

From: Meteorin-like/Meteorin-β protects LPS-induced acute lung injury by activating SIRT1-P53-SLC7A11 mediated ferroptosis pathway

Fig. 6

Metrnβ knockdown exacerbated LPS-induced MLE-12 cell injury and ferroptosis. MLE-12 cells were transfected with Metrnβ siRNA and treated with LPS. A Protein levels of Metrnβ after Metrnβ siRNA transfection (n = 4). B Levels of proinflammatory markers in MLECs (n = 6). C The viability of MLECs (n = 6). D Fe2+ levels in MLECs (n = 6). E MDA levels in MLECs (n = 6). F GSH levels in MLECs (n = 6). *P < 0.05 vs. the ScRNA-CON group. #P < 0.05 vs. the ScRNA-LPS group

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Molecular Medicine

ISSN: 1528-3658