Fig. 8
Ferroptosis inhibition or activation abolished Metrnβ-mediated effects in vitro. MLE-12 cells were transfected with Ad-Metrnβ or treated with VAD-fmk (10 mM). A Levels of proinflammatory markers in MLECs (n = 6). B The viability of MLECs (n = 6). C Fe2+ levels in MLECs (n = 6). D MDA levels in MLECs (n = 6). F GSH levels in MLECs (n = 6). *P < 0.05 vs. the CON group, #P < 0.05 vs. the LPS group. &P < 0.05. NS: no significant