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Fig. 5 | Molecular Medicine

Fig. 5

From: Oral probiotics increased the proportion of Treg, Tfr, and Breg cells to inhibit the inflammatory response and impede gestational diabetes mellitus

Fig. 5

Differential gene analysis of transcriptomic sequencing in GDM and healthy individuals. A Volcano map of the DEGs in GDM mice (n = 3) and normal control mice (n = 3) by transcriptomic sequencing (Blue represents the downregulated genes, and red represents the upregulated genes). B PPI network of the proteins encoded by the DEGs in GDM mice (n = 3) and normal control mice (n = 3) through transcriptome sequencing analysis (The size represents the degree value, and the color from deep to shallow represents combined_score from low to high). C Leptin protein level in the peripheral blood of GDM mice (n = 3) and normal control mice (n = 3) measured by ELISA (*** p < 0.05). D Functional analysis of the gut microbiota of GDM mice (n = 3) and normal control mice (n = 3)

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Molecular Medicine

ISSN: 1528-3658