Skip to main content
Fig. 5 | Molecular Medicine

Fig. 5

From: RILP inhibits tumor progression in osteosarcoma via Grb10-mediated inhibition of the PI3K/AKT/mTOR pathway

Fig. 5

RILP induces OS cell autophagy by inhibiting PI3K/AKT/mTOR pathway. A, B Representative transmission electron micrographs autophagic vesicles in 143B and U2OS cells stably transfected with shNC/shRILP and LV-Control/LV-RILP. C–E The protein expression level of Beclin1 and p62 in osteosarcoma cells was detected after treated with 740Y-P or not. GAPDH was used as a loading control. F, G Representative images and quantitative analysis of Beclin1 immunofluorescence intensity in osteosarcoma cells stably transfected with RILP or not, scale bar: 200 μm. *P < 0.05, **P < 0.01

Back to article page

Molecular Medicine

ISSN: 1528-3658