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Fig. 6 | Molecular Medicine

Fig. 6

From: RILP inhibits tumor progression in osteosarcoma via Grb10-mediated inhibition of the PI3K/AKT/mTOR pathway

Fig. 6

The effect of RILP expression can affect migration and invasion of osteosarcoma cells that is mediated by autophagy. A–C Wound healing assay comparing the motility of osteosarcoma cells after treated with 3-methyladenine or not, scale bar: 200 μm. D, E Transwell invasion assay was performed to compare the invasion ability of osteosarcoma cells after treated with 3-methyladenine or not, scale bar: 400 μm. F–H Western blot analysis was applied to measure the protein expression level of E-cadherin, N-cadherin and Vimentin. GAPDH was used as a loading control. *P < 0.05, **P < 0.01

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Molecular Medicine

ISSN: 1528-3658