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Fig. 1 | Molecular Medicine

Fig. 1

From: Interaction between N6-methyladenosine modification and the tumor microenvironment in colorectal cancer

Fig. 1

Classification and composition of m6A regulators. m6A “writers” include METTL3, METTL14, WTAP, METTL16, KIAA1429, RBM15, RBM15B, CBLL1, ZC3H13, which are responsible for structure stabilization and catalysis. m6A “erasers” include FTO, ALKBH5, ALKBH3, which are responsible for demethylation. HNRNPA2B1, HNRNPC, and IGF2BPs are responsible for recognizing m6A sites and mediating RNA splicing, translation, processing, structural transformation, and stabilization

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