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Fig. 3 | Molecular Medicine

Fig. 3

From: Interaction between N6-methyladenosine modification and the tumor microenvironment in colorectal cancer

Fig. 3

m6A modification interacts with the hypoxic microenvironment of CRC. METTL3 mediates the progression of EMT by enhancing the expression of HIF-1α. YTHDF1 is induced by the hypoxic microenvironment and promotes CRC progression by targeting HIF-1α. FTO is inhibited by the hypoxic microenvironment and suppresses CRC metastasis by suppressing the expression of MTA1

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Molecular Medicine

ISSN: 1528-3658