Fig. 1From: The benefits of rehabilitation exercise in improving chronic traumatic encephalopathy: recent advances and future perspectivesThe pathological mechanisms of CTE. The accumulation of abnormal protein deposition, reduction in synaptic plasticity, and abnormal activation of the inflammatory reaction, reduced microcirculation function, and impaired blood–brain barrier are the main pathological features of CTE. It worsens the brain microenvironment and leads to extensive neuronal degenerationBack to article page