Fig. 1

L-BAIBA preconditioning protects the lung from I/R injury

(A): Mouse survival rates after lung I/R injury with or without L-BAIBA treatment (n = 15, Log-rank (Mantel-Cox) test was used to analyze survival rate). (B): Representative histopathological images of I/R-induced lung injury in mice with or without L-BAIBA treatment (n = 12, Kolmogorov-Smirnov test was used for normality test and Kruskal-Wallis test was used for statistical analysis). (C): The degree of lung edema in mice was evaluated by the ratio of lung wet and dry weights (n = 5, Kolmogorov-Smirnov test was used for normality test. ANOVA was used for statistical analysis and LSD was used for post hoc analysis). (D and E): The arterial blood PaO₂(D) and PaCO₂(E) were used to evaluate the degree of hypoxemia (n = 5). Kolmogorov-Smirnov test was used for normality test. ANOVA was used for statistical analysis and LSD (D) or Tamhane test (E) was used for post hoc analysis). The values are presented as mean ± SD (*P < 0.05 vs. Sham, #P < 0.05 vs. I/R only)