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Fig. 7 | Molecular Medicine

Fig. 7

From: Targeted inhibition of CX3CL1 limits podocytes ferroptosis to ameliorate cisplatin-induced acute kidney injury

Fig. 7

CX3CL1 reduced ER stress, which in turn alleviated cisplatin-induced podocyte damage. A The protein expression levels associated with ER stress were evaluated by Western blotting. B The levels of podocyte-specific proteins were evaluated by Western blotting. C CX3CL1, HIF1A, and HO-1 levels were evaluated by Western blot. (ER, endoplasmic reticulum; HIF1A, hypoxia inducible factor 1-alpha; HO-1, heme oxygenase-1; P value was calculated by one-way analysis of variance and Tukey’s test. *p < 0.05, **p < 0.01, and ***p < 0.001 vs the control group; #p < 0.05, ##p < 0.01, and ###p < 0.001 vs the Cis group)

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