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Fig. 3 | Molecular Medicine

Fig. 3

From: Mechanism of RhoA regulating benign prostatic hyperplasia: RhoA-ROCK-β-catenin signaling axis and static & dynamic dual roles

Fig. 3

RhoA inhibits the apoptosis of WPMY-1 and BPH-1 cells, but do not affect the cell cycle. A Flow cytometry analysis of the cell apoptosis in WPMY-1 and BPH-1 cells after RhoA knockdown. B Flow cytometry analysis of the cell apoptosis in WPMY-1 and BPH-1 cells after RhoA overexpression. C Immunoblot assay of proteins in relation to cell apoptosis (BAX and Bcl-2) in WPMY-1 and BPH-1 cells after RhoA knockdown. D Immunoblot assay of proteins in relation to cell apoptosis in WPMY-1 and BPH-1 cells after RhoA overexpression. E Flow cytometry analysis of the cell cycle in WPMY-1 and BPH-1 cells after RhoA knockdown. F Flow cytometry analysis of the cell cycle in WPMY-1 and BPH-1 cells after RhoA overexpression. Data were expressed as mean ± SD. ns means no significant difference, **p < 0.01, ***p < 0.001

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