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Fig. 1 | Molecular Medicine

Fig. 1

From: Vitexin attenuates chronic kidney disease by inhibiting renal tubular epithelial cell ferroptosis via NRF2 activation

Fig. 1

Vitexin alleviated renal fibrosis in the UUO mouse model. (A) PAS staining of kidney tissues and the renal injury index were calculated; magnification ×400; scale bar: 20 μm. Renal fibrosis was evaluated by (B) Sirius red and (C) IHC staining of collagen I. The images were quantified using ImageJ. (D) Representative protein expression of fibronectin, α-SMA and E-cadherin in the renal tissues of mice, as determined by Western blotting. Semiquantification of the blots is shown (right). The data are shown as the mean ± S.D. of each mouse (n = 6 mice in each group). ****P < 0·0001, ***P < 0·001, ns: no significance (analyzed by one-way ANOVA).

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Molecular Medicine

ISSN: 1528-3658