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Table 1 Baseline comparison of demographic and clinical characteristics between the PTB and non-PTB groups

From: Performance of the MeltPro TB assay as initial test for diagnosis of pulmonary tuberculosis with drug-resistance detection

 

PTB (n = 875)

Non-PTB (n = 408)

P-value

Characteristics

   

Sex

  

0.344

Male, n (%)

522 (59.7%)

232 (56.9%)

 

Female, n (%)

353 (40.3%)

176 (43.1%)

 

Age, years

42.7 ± 7.3

44.5 ± 7.4

0.263

BMI, kg/m2

20.2 ± 2.8

21.1 ± 3.2

0.143

QuantiFERON-TB ( +), n (%)

706 (80.7%)

119 (29.2%)

 < 0.01

Presenting symptoms or signs

No special clinical symptoms, n (%)

194 (22.2%)

72 (17.6%)

0.065

Non-productive cough, n (%)

562 (64.2%)

276 (67.6%)

0.231

Productive cough, n (%)

435 (49.7%)

225 (55.1%)

0.072

Chest tightness and/or wheezing, n (%)

177 (20.2%)

98 (24.0%)

0.123

Fever, n (%)

161 (18.4%)

91 (22.3%)

0.113

Fatigue, n (%)

110 (12.6%)

44 (10.8%)

0.407

Thoracalgia, n (%)

93 (10.6%)

52 (12.7%)

0.265

Hemoptysis and/or blood in phlegm, n (%)

92 (10.5%)

49 (12.0%)

0.444

Inappetence, n (%)

59 (6.7%)

19 (4.7%)

0.168

Weight loss, n (%)

47 (5.4%)

18 (4.4%)

0.498

Radiological characteristics

   

Involvement extent of lung lesions

  

0.111

 ≤ 3 lobes, n (%)

621 (71.0%)

307 (75.2%)

 

 ≥ 4 lobes, n (%)

254 (29.0%)

101 (24.8%)

 

Cavitary, n (%)

245 (28.0%)

98 (24.0%)

0.134

Underlying disease

   

COPD, n (%)

43 (4.9%)

23 (5.6%)

0.585

Bronchiectasis, n (%)

66 (7.5%)

37 (9.1%)

0.349

Diabetes, n (%)

132 (15.1%)

22 (5.4%)

 < 0.01

Previous history of tuberculosis, n (%)

224 (25.6%)

96 (23.5%)

0.425

Specimen

  

0.521

Sputum, n (%)

657 (75.1%)

312 (76.5%)

 

BALF, n (%)

187 (21.4%)

78 (19.1%)

 

Pulmonary puncture fluid, n (%)

31 (3.5%)

18 (4.4%)

 
  1. PTB pulmonary tuberculosis, BMI Body mass index, COPD chronic obstructive pulmonary disease, BALF bronchoalveolar lavage fluid