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Fig. 6 | Molecular Medicine

Fig. 6

From: Exosomal circCOL1A1 promotes angiogenesis via recruiting EIF4A3 protein and activating Smad2/3 pathway in colorectal cancer

Fig. 6

Exosomal circCOL1A1 promotes angiogenesis through Smad2/3 pathway. HUVECs were transfected with pcDNA3.1-NC or pcDNA3.1-EIF4A3, followed by treatment with CRC cell-derived exosomes. (A) The protein levels of VEGFR and p-Smad2, Smad2, p-Smad3, and Smad3 were detected by western blot. *, P < 0.05, **, P < 0.01, ***, P < 0.001

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Molecular Medicine

ISSN: 1528-3658