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Fig. 8 | Molecular Medicine

Fig. 8

From: PP121, a dual inhibitor of tyrosine and phosphoinositide kinases, relieves airway hyperresponsiveness, mucus hypersecretion and inflammation in a murine asthma model

Fig. 8

PP121 inhibited VEGF and MAPK/Akt signaling pathways in lung tissues. A–C The western blot band (left panel) and bar graph (right panel) show the ratio of p-VEGR2 to VEGFR2, p-Akt to Akt and p-p38 MAPK to p38 MAPK in the control, asthma, Dex and PP121 groups, respectively. *p < 0.05; **p < 0.01

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Molecular Medicine

ISSN: 1528-3658